P5171
Endoproteinase Arg-C from mouse submaxillary gland
Type XX-S, lyophilized powder, 250-800 units/mg protein (Lowry)
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About This Item
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352204
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type
Type XX-S
Quality Level
form
lyophilized powder
specific activity
250-800 units/mg protein (Lowry)
composition
Protein, 3.0-7.0%
analyte chemical class(es)
amino acids
storage temp.
2-8°C
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Unit Definition
One unit will hydrolyze 1.0 μmole of Nα-p-tosyl-L-arginine methyl ester per min at pH 8.0 at 25 °C.
Physical form
Lyophilized powder containing NaCl and sodium acetate
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
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Yoshika Yasuda et al.
Biological & pharmaceutical bulletin, 34(9), 1518-1521 (2011-09-02)
Oral formulation of tissue kallikrein consists primarily of porcine pancreatic kallikrein (PPK) and is used to improve peripheral circulation, menopausal symptoms, and impaired chorioretinal circulation. Although gastrointestinal absorption of tissue kallikrein after oral administration has been reported in nonclinical and
Ling Liu et al.
Biochemical and biophysical research communications, 407(2), 283-287 (2011-03-08)
Systemic or local delivery of human tissue kallikrein gene (hTK) has been shown to be an effective strategy to alleviate cerebral ischemia/reperfusion (I/R) injury, and tissue kallikrein (TK) administration can suppress glutamate- or acidosis-mediated neurotoxicity in vitro. In the present
Michael E Stern et al.
Investigative ophthalmology & visual science, 53(4), 2062-2075 (2012-03-08)
The purpose of this study was to determine if autoantibodies play a role in the immunopathogenesis of experimental dry eye disease. Dry eye was induced by exposing female C57BL/6 wild-type mice or hen egg lysozyme B-cell receptor transgenic mice to
Waleska K Martins et al.
BMC medical genomics, 4, 76-76 (2011-10-29)
A wide variety of high-throughput microarray platforms have been used to identify molecular targets associated with biological and clinical tumor phenotypes by comparing samples representing distinct pathological states. The gene expression profiles of human cutaneous melanomas were determined by cDNA
Ibeth Guevara-Lora et al.
Peptides, 32(6), 1193-1200 (2011-05-10)
Bradykinin-related peptides, kinins, ubiquitously occur in the nervous system and together with other pro-inflammatory mediators contribute to pathological states of that tissue such as edema and chronic pain. In the current work we characterized the kinin-forming system of neuronal cells
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