N7758
Naloxone hydrochloride dihydrate
≥98% (TLC and titration), powder
About This Item
Recommended Products
Quality Level
assay
≥98% (TLC and titration)
form
powder
optical activity
[α]25/D −178.6°, c = 2.5 in H2O(lit.)
color
white to off-white
solubility
ethanol: 3.3 mg/mL
H2O: 50 mg/mL
storage temp.
2-8°C
SMILES string
O.O.Cl.Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC=C
InChI
1S/C19H21NO4.ClH.2H2O/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;;;/h2-4,14,17,21,23H,1,5-10H2;1H;2*1H2/t14-,17+,18+,19-;;;/m1.../s1
InChI key
TXMZWEASFRBVKY-IOQDSZRYSA-N
Gene Information
human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988) , OPRS1(10280)
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Application
- isotonic saline and injected subcutaneously into experimental rats to study its involvement with withdrawal syndrome in morphine-dependent rats
- as opioid receptor antagonist to examine the role of the endogenous opioid system in infantile amnesia for contextual fear
- as a reference neutral antagonist to define the maximum effect (Emax) of the system
Biochem/physiol Actions
Features and Benefits
Caution
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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