Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

N3529

Sigma-Aldrich

NAN-190 hydrobromide

Synonym(s):

1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C23H27N3O3 · HBr
CAS Number:
115338-32-4
Molecular Weight:
474.39
MDL number:
MFCD00078590
UNSPSC Code:
12352200
PubChem Substance ID:
24278108

SMILES string

Br.COc1ccccc1N2CCN(CCCCN3C(=O)c4ccccc4C3=O)CC2

InChI

1S/C23H27N3O3.BrH/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28;/h2-5,8-11H,6-7,12-17H2,1H3;1H

InChI key

AXRUEPFPTQYHQD-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350)

Biochem/physiol Actions

Potent 5-HT1A serotonin receptor antagonist active in the nM range.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

James Oluwagbamigbe Fajemiroye et al.
Journal of ethnopharmacology, 141(3), 872-877 (2012-04-05)
Medicinal applications of Pimenta pseudocaryophyllus infusion as a diuretic and aphrodisiac agent as well as tranquilizer in the form of tea for the treatment of emotional tension in Brazilian folk medicine has been in practice since time immemorial. Despite its
J E Duffy-Whritenour et al.
Brain, behavior, and immunity, 22(2), 257-264 (2007-09-26)
An immunomodulatory role for serotonin (5-HT) has been demonstrated in mammals and evidence for a similar role for 5-HT has recently emerged in fish. However, as limited studies are available, discrepancies often exist regarding the role of 5-HT in the
R L Dennis et al.
Poultry science, 87(4), 612-620 (2008-03-15)
Serotonin (5-HT) regulates aggressive behavior via binding to its receptors, such as 5-HT1A and 1B, in humans and rodents. Here we investigate the heritable components of 5-HT regulation of aggressiveness in chickens, utilizing 3 distinct genetic strains. In this study
E J Kessler et al.
Neuroscience, 154(4), 1187-1194 (2008-06-10)
Health problems can arise from de-synchrony between the external environment and the endogenous circadian rhythm, yet the circadian system is not able to quickly adjust to large, abrupt changes in the external daily cycle. In this study, we investigated the
Jaime Pei Pei Foong et al.
Neuroreport, 20(3), 325-330 (2009-02-05)
Serotonin (5-HT) plays a significant role in the regulation of intestinal secretion of water and electrolytes. The initial aim of this study was to use intracellular recording and specific antagonists to identify roles of 5-HT1A and 5-HT7 receptors of submucosal
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service