MAK530
Alkaline Phosphatase (ALP) Assay Kit
sufficient for 100 fluorometric tests
Synonym(s):
Fluorometric Alkaline Phosphatase Assay Kit
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
Quality Level
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders
shipped in
wet ice
storage temp.
−20°C
General description
Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.
Features and Benefits
- Detection limit of 0.02 U/L
- Compatible with high-throughput handling systems.
Suitability
The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.
Principle
The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
Certificates of Analysis (COA)
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