The solubility of this product is tested in chloroform at 50 mg/mL. Solution stability has not been determined, however the acetate form is unstable in solution and should be prepared fresh. The end user would have to validate solution stability of this compound experimentally. The NIH lists the material as being soluble in ethanol, methanol, ether, and acetone. Please see the link below to review this publication:
https://pubchem.ncbi.nlm.nih.gov/compound/Medroxyprogesterone#section=Color-Form
M6013
Medroxyprogesterone
Synonym(s):
17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C22H32O3
CAS Number:
Molecular Weight:
344.49
Beilstein/REAXYS Number:
2510965
EC Number:
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
biological source:
synthetic (organic)
form:
powder
assay:
≥98% (HPLC)
Pricing and availability is not currently available.
Recommended Products
biological source
synthetic (organic)
assay
≥98% (HPLC)
form
powder
solubility
chloroform: 50 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
SMILES string
[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O
InChI
1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
InChI key
FRQMUZJSZHZSGN-HBNHAYAOSA-N
Gene Information
rat ... Ar(24208)
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Caution
Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.
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Product No.
Description
Pricing
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Clinical significance of differences in bioavailability of medroxyprogesterone acetate preparations.
A D Stockdale et al.
Clinical pharmacokinetics, 16(3), 129-133 (1989-03-01)
M F Fung et al.
Obstetrics and gynecology, 78(6), 1033-1038 (1991-12-01)
We conducted a retrospective review of 44 patients with metastatic or recurrent endometrial carcinoma treated with cisplatin, doxorubicin, cyclophosphamide, and medroxyprogesterone acetate. Thirty-six women had metastatic disease; eight had recurrent disease. In the metastatic group, 12 women had positive peritoneal
Nioka C Chisholm et al.
Endocrinology, 153(10), 4874-4882 (2012-08-21)
Menopausal women often initiate hormone treatment to alleviate the symptoms of menopause. Research suggests that these treatments also affect cognition, and studies in young animals indicate that hormone treatment can alter several neuroanatomical measures. However, very little is known about
Adarsh J Sai et al.
Menopause (New York, N.Y.), 18(10), 1101-1112 (2011-06-30)
The aim of this study was to examine the effect of conjugated equine estrogens alone (ET), conjugated equine estrogens + medroxyprogesterone (EPT), calcitriol alone, calcitriol + EPT/ET, or placebo on serum lipid profile and analyze the interaction with estrogen receptor-α
James Hassell et al.
Hormones and behavior, 60(2), 219-225 (2011-06-04)
Progestins and antiprogestins are widely used therapeutic agents in humans. In many cases, these are indicated for the treatment of reproductive activities. However, progesterone has widespread physiological effects including a reduction of the response to stress. We have reported that
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is there is any other solution can be used to dissolve the Medroxyprogesterone and whats the tempreture we need to use for stoarge after dissolving the Medroxyprogesterone
1 answer-
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