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Key Documents

M4542

Sigma-Aldrich

Melanin Concentrating Hormone rat

≥90% (HPLC)

Synonym(s):

MCH

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About This Item

Empirical Formula (Hill Notation):
C105H160N30O26S4
CAS Number:
Molecular Weight:
2386.84
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.32

biological source

synthetic (organic)

assay

≥90% (HPLC)

form

powder

composition

Peptide content, ≥70%

solubility

water: 1 mg/mL, clear, colorless

UniProt accession no.

shipped in

ambient

storage temp.

−20°C

SMILES string

CSCC[C@@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(C)C)NC1=O)C(C)C)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc6ccccc6)NC(=O)[C@@H](N)CC(O)=O

InChI

1S/C105H160N30O26S4/c1-53(2)42-70-86(144)118-50-80(138)119-64(24-16-36-114-103(108)109)90(148)133-83(55(5)6)100(158)130-73(45-58-28-30-60(136)31-29-58)93(151)124-69(26-18-38-116-105(112)113)101(159)135-39-19-27-78(135)99(157)132-77(98(156)128-74(46-59-49-117-63-23-15-14-22-61(59)63)95(153)121-66(32-33-79(107)137)91(149)134-84(56(7)8)102(160)161)52-165-164-51-76(97(155)123-68(35-41-163-10)88(146)126-70)131-87(145)65(25-17-37-115-104(110)111)120-92(150)71(43-54(3)4)127-89(147)67(34-40-162-9)122-96(154)75(48-82(141)142)129-94(152)72(44-57-20-12-11-13-21-57)125-85(143)62(106)47-81(139)140/h11-15,20-23,28-31,49,53-56,62,64-78,83-84,117,136H,16-19,24-27,32-48,50-52,106H2,1-10H3,(H2,107,137)(H,118,144)(H,119,138)(H,120,150)(H,121,153)(H,122,154)(H,123,155)(H,124,151)(H,125,143)(H,126,146)(H,127,147)(H,128,156)(H,129,152)(H,130,158)(H,131,145)(H,132,157)(H,133,148)(H,134,149)(H,139,140)(H,141,142)(H,160,161)(H4,108,109,114)(H4,110,111,115)(H4,112,113,116)/t62-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-/m0/s1

InChI key

MWLPXSMFEPHETN-QRXCLJFASA-N

Gene Information

rat ... Pmch(24659)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Wenting Cheng et al.
Talanta, 219, 121242-121242 (2020-09-06)
Growing evidence suggests that exosomes-encapsulated miRNAs detection is of paramount significance in early diagnostics of cancer due to protection from degradation by ribonuclease. However, exosomal microRNAs with low abundance and subtle variation have restricted their clinical application. Herein, an electrochemical
Melanin-concentrating hormone induces insulin resistance through a mechanism independent of body weight gain
Marcio P
The Journal of Endocrinology (2005)
The role of melanin concentrating hormone (MCH) in the central chemoreflex: a knockdown study by siRNA in the lateral hypothalamus in rats.
Li N
PLoS ONE (2014)
Peng Miao et al.
Small (Weinheim an der Bergstrasse, Germany), 16(47), e2004518-e2004518 (2020-11-04)
miRNAs, a class of endogenous noncoding RNAs, are involved in many crucial biological processes, which have emerged as a new set of biomarkers for disease theranostics. Exploring efficient signal amplification strategy is highly desired to pursue a highly sensitive miRNA
Melanin concentrating hormone induces hippocampal acetylcholine release via the medial septum in rats.
Peptides (2013)

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