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L9634

Sigma-Aldrich

Laminarin from Laminaria digitata

polysaccharide substrate for laminarinase

Synonym(s):

Laminaran

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

algae (Laminaria digitata)

form

powder

optical activity

[α]20/D -20 to -5 °, c = 4% (w/v) in water

color

beige

useful pH range

5

solubility

water: 10 mg/mL, clear to slightly hazy, colorless to light yellow

storage temp.

room temp

InChI

1S/C18H32O16/c19-1-4-7(22)10(25)11(26)17(31-4)34-15-9(24)6(3-21)32-18(13(15)28)33-14-8(23)5(2-20)30-16(29)12(14)27/h4-29H,1-3H2/t4-,5-,6-,7-,8-,9-,10+,11-,12-,13-,14+,15+,16?,17?,18?/m1/s1

InChI key

DBTMGCOVALSLOR-VPNXCSTESA-N

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General description

The fronds of Laminaria and Saccharina species contain laminarin, a low molecular weight storage glucan. It is localized to the vacuoles. Laminarin structure contains β-(1,6)-intrachain linked (1,3)-β-d-glucan.

Application

Laminarin from Laminaria digitata has been used:
  • as a stimulant to study its effect on the respiratory burst using haemocytes of P. vannamei
  • as a carbon source to study its effect on enzyme production using Pichia membranifaciens culture
  • as a carbon source for Polaribacter sp. culture

Biochem/physiol Actions

Laminarin is a biologically active compound effective against inflammation. It serves as an antioxidant and anticoagulant. Laminarin also inhibits apoptosis and tumor development. It acts as a predominant source of carbon among aquatic prokaryotes.
Laminarin is a polysaccharide of glucose found in brown algae and utilized as a food reserve.

Other Notes

Polysaccharide; primarily poly(β-Glc-[1→3]) with some β-(1→6) interstrand linkages and branch points.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Substrates

Substrate for laminarinase.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Michael H Huesemann et al.
Bioresource technology, 108, 305-309 (2012-01-27)
The objective of this study was to subject mannitol, either as a sole carbon source or in combination with glucose, and aqueous extracts of the kelp Saccharina spp., containing mannitol and laminarin, to acetone-butanol fermentation by Clostridium acetobutylicum (ATCC 824).
Manuel Martinez-Garcia et al.
PloS one, 7(4), e35314-e35314 (2012-04-27)
Microbial hydrolysis of polysaccharides is critical to ecosystem functioning and is of great interest in diverse biotechnological applications, such as biofuel production and bioremediation. Here we demonstrate the use of a new, efficient approach to recover genomes of active polysaccharide
Tomasz Lipinski et al.
Journal of immunology (Baltimore, Md. : 1950), 190(8), 4116-4128 (2013-03-22)
In a previous attempt to generate a protective vaccine against Candida albicans, a β-mannan tetanus toxoid conjugate showed poor immunogenicity in mice. To improve the specific activation toward the fungal pathogen, we aimed to target Dectin-1, a pattern-recognition receptor expressed
Niches of two polysaccharide-degrading Polaribacter isolates from the North Sea during a spring diatom bloom
Xing P, et al.
The ISME Journal, 9(6), 1410-1410 (2015)
Sung-Yong Kim et al.
Frontiers in plant science, 11, 1043-1043 (2020-08-06)
Callose deposition is induced in plants by various stress factors such as when plants are attacked by herbivores and pathogens. In the case of aphids, callose plugging of aphid-damaged phloem sieve tubes is expected to reduce aphid access to the

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