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I3386

Sigma-Aldrich

Imidazole hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C3H4N2 · HCl
CAS Number:
1467-16-9
Molecular Weight:
104.54
Beilstein/REAXYS Number:
3678283
MDL number:
MFCD00012695
UNSPSC Code:
12161700
eCl@ss:
39161001
PubChem Substance ID:
24896034
NACRES:
NA.25

assay

≥98% (TLC)
≥98.5% (perchloric acid titration)

Quality Level

200

form

powder

pH

9.0-10.0

mp

158-161 °C (lit.)

solubility

methanol: 50 mg/mL, clear, colorless to faintly yellow

application(s)

diagnostic assay manufacturing

SMILES string

Cl.c1c[nH]cn1

InChI

1S/C3H4N2.ClH/c1-2-5-3-4-1;/h1-3H,(H,4,5);1H

InChI key

JDIIGWSSTNUWGK-UHFFFAOYSA-N

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Application

Imidazole hydrochloride has been used:
  • in double immunohistochemistry
  • to determine the activity of octopine dehydrogenase (ODH) in Mytilus galloprovincialis
  • to study the cytoskeletal features during in vitro fertilization after intracytoplasmic sperm injection (ICSI) among humans
  • as a reagent in the synthesis of a probe for monitoring herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene expression in rodents

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Exploring the cytoskeleton during intracytoplasmic sperm injection in humans
Microinjection: Methods and Applications, 189-206 (2009)
The alpha4beta2 nicotine acetylcholine receptor agonist is pronicline induces c-Fos expression in selective regions of the rat forebrain
Jacobsen J, et al.
Neuroscience Letters, 515(1), 7-11 (2012)
Biochemical responses of the marine mussel Mytilus galloprovincialis to petrochemical environmental contamination along the North-western coast of Portugal
Lima I, et al.
Chemosphere, 66(7), 1230-1242 (2007)
Jin-Woo Kim et al.
Biotechnology for biofuels, 9, 265-265 (2016-12-19)
2,3-Butanediol (2,3-BD) is a promising compound for various applications in chemical, cosmetic, and agricultural industries. Pyruvate decarboxylase (Pdc)-deficient Saccharomyces cerevisiae is an attractive host strain for producing 2,3-BD because a large amount of pyruvate could be shunted to 2,3-BD production
Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI.
Bar-Shir A
Nature Protocols, 8(12), 2380-2380 (2013)
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