H7786
Hck human
recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution
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About This Item
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recombinant
expressed in baculovirus infected insect cells
Quality Level
form
buffered aqueous glycerol solution
specific activity
≥350 units/mg protein
mol wt
58 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... HCK(3055)
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Biochem/physiol Actions
Hck is a member of the Src family of non-receptor associated protein tyrosine kinases (PTK).
Unit Definition
One unit will transfer 1 nanomole of phosphate per minute using polyE4Y as the substrate at pH 7.5 at 30 °C
Physical form
Solution in 50 mM Tris pH 7.5, containing 0.05 mM EDTA, 1mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Journal of cell science, 115(Pt 1), 81-89 (2002-01-22)
In macrophages, lysosomes are suspected to have a heterogenous population of vesicles. This study was thus undertaken to identify and to characterize lysosomal compartments in human macrophages. Hck is a Src-family tyrosine kinase associated with secretory lysosomes in neutrophils and
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