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GW22770

Sigma-Aldrich

Anti-MAPK7 (ab2) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-22770

technique(s)

western blot: suitable

NCBI accession no.

NP_002740.2

UniProt accession no.

Q13164

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPK7(5598)

Immunogen

Immunogen Sequence: GI # 20986497, sequence 341-570
Recombinant mitogen-activated protein kinase 7 isoform 1

Application

Anti-MAPK7 (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Mitogen-activated protein kinase 7 (also known as MAP kinase 7) is an enzyme encoded by the MAPK7 gene in humans and is mapped to chromosome 17 band p11.2. It belongs to mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. MAPK7 is involved in degeneration of nucleus pulposus. Expression of MAPK7 may act as a valuable indicator for predicting lung cancer risk in smokers.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Weiguo Liang et al.
Biochemical and biophysical research communications, 449(4), 466-470 (2014-05-27)
Extracellular-signal-regulated kinase 5 (ERK5) is a member of the mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. However, the expression of ERK5 and its role in degenerated
Fuman Qiu et al.
Mutagenesis, 28(5), 561-567 (2013-06-28)
Mitogen/extracellular signal-regulated kinase-5 (MEK5)/extracellular signal-regulated protein kinase-5 (ERK5) pathway plays a pro-oncogenic role in tumourigenesis by anticell apoptosis, promoting cell proliferation and differentiation in response to extracellular stimuli. As overexpressed MEK5/ERK5 is involved in the development of lung cancer, we
Assignment of big MAP kinase (PRKM7) to human chromosome 17 band p11.2 with somatic cell hybrids.
S M Purandare et al.
Cytogenetics and cell genetics, 83(3-4), 258-259 (1999-03-11)

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