G4274
Globoside from human erythrocytes
≥95%
Synonym(s):
Globotetraosylceramide
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About This Item
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biological source
human erythrocytes
assay
≥95%
form
film
functional group
amide
hydroxyl
shipped in
ambient
storage temp.
−20°C
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Josefine Betz et al.
Biological chemistry, 393(3), 133-147 (2012-06-22)
Membrane microdomain association of the glycosphingolipids (GSLs) globotriaosylceramide (Gb3Cer) and globotetraosylceramide (Gb4Cer), the highly and less effective receptors, respectively, for Shiga toxins (Stxs), is assumed as a functional requirement for Stx-mediated cytotoxicity. In a previous study, we demonstrated predominant localization
D H Jones et al.
Biochemistry, 36(28), 8539-8547 (1997-07-15)
Recognition of macromolecules by glycosphingolipids is closely correlated with the nature of the glycolipid carbohydrate; however, it is also thought to be secondarily modulated by the structure of the single fatty acid. In the present work, we sought insight into
Yunsen Li et al.
Glycobiology, 18(2), 158-165 (2007-12-07)
Glycosphingolipids serve as ligands for receptors involved in signal transduction and immune recognition, as exemplified by isoglobotrihexosylceramide, an antigenic ligand for T cell receptors. Mechanistic studies on the regulation of isoglobotrihexosylceramide require biochemical measurement of its lysosomal precursor, isoglobotetraglycosylceramide. It
Tetsuya Okuda et al.
Glycoconjugate journal, 27(2), 287-296 (2010-01-19)
In several vascular inflammatory reactions (i.e. immunity and thrombosis) inflammatory mediators lead to the activation of vascular endothelial cells (EC). To date, a number of functional molecules induced on the surface of activated-EC have been identified. We report here that
Kiyotaka Nishikawa
Archivum immunologiae et therapiae experimentalis, 59(4), 239-247 (2011-06-07)
Infection with Shiga toxin (Stx)-producing Escherichia coli (STEC), including O157:H7, causes bloody diarrhea and hemorrhagic colitis in humans, occasionally resulting in fatal systemic complications, such as neurological damage and hemolytic-uremic syndrome. Because Stx is a major virulence factor of the
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