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Key Documents

G3892

Sigma-Aldrich

Gly-Arg-Gly-Asp

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C14H25N7O7
CAS Number:
Molecular Weight:
403.39
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

NCC(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC(O)=O)C(O)=O

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Other Notes

Tetrapeptide overlapping the cell-attachment domain of fibronectin (the cell-attachment promoting activity has been localized to the tetrapeptide Arg-Gly-Asp-Ser).

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Ignacy Z Siemion et al.
Peptides, 24(8), 1109-1115 (2003-11-13)
Continuing our research on Mycobacteria kansasii phagocytosis inhibition, we have examined in that context three series of peptides derived from the RGDVY and GRGD sequences. It was found that the levels of the inhibitory activity depend on the amino acid
Tze-Wen Chung et al.
Biomaterials, 23(24), 4803-4809 (2002-10-04)
To improve ECs adhesion and growth on chitosan, cell adhesive peptide Gly-Arg-Gly-Asp (GRGD) was photochemically grafted to its surface. Grafting 0.025 M of GRGD-SANPAH (N-Succinimidyl-6-[4'-azido-2'-nitrophenylamino]-hexanoate) solutions to chitosan and tripolyphosphate anhydrous crosslinked chitosan (chitosan-TPP) surfaces was performed by surface adsorption
Shoei-Shen Wang et al.
Journal of biomedical materials research. Part A, 91(3), 753-761 (2008-12-04)
Accelerated thrombolysis by pressure-driven permeation has been demonstrated in in vitro and in vivo animal models by using plasminogen activators (PAs) encapsulated liposomes or PEG microparticles. Recent reports have also described acceleration of thrombolysis using tissue type PA (t-PA) encapsulated
Y S Lin et al.
Artificial organs, 25(8), 617-621 (2001-09-05)
To improve endothelial cell adhesion and growth on the surface of polyethylene glycol modified polyurethane (PU-PEG), cell adhesive peptide Gly-Arg-Gly-Asp (GRGD) was photochemically grafted to the surface. The surface grafted GRGD-N-Succinimidyl-6-[4'-azido-2'-nitrophenylamino]hexanoate (SANPAH) on a PU-PEG surface was performed by adsorption
Covalently attached GRGD on polymer surfaces promotes biospecific adhesion of mammalian cells.
S P Massia et al.
Annals of the New York Academy of Sciences, 589, 261-270 (1990-01-01)

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