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EHU065471

Sigma-Aldrich

MISSION® esiRNA

targeting human DOPEY1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCACGTTGCAGTCACAACTTCTTAAGGTGCTTCAGAGGCTGATTGTTCTAGAACACAGAGTAATGACTATTCCTGAAGAGAATGAAACAGGTTTTGATTTTGTTGTATCTGACTTAGAACACATCAGTCCCCATCAACCCATGACTTCTCTTCAGTATTTGCATGCTCAGCCAATCACATGTCAAGGCATGTTCCTCTGTGCAGTGATACGAGCTTTGCATCAGCACTGTGCATGTAAGATGCACCCACAATGGATTGGTTTAATCACATCTACTCTGCCTTACATGGGAAAAGTTCTGCAGAGAGTGGTTGTTTCTGTGACACTACAACTGTGCAGAAATTTAGATAATCTAATTCAGCAGTACAAATACGAAACAGGATTATCTGATAGTAGGCCTCTGTGGATGGCATCAAT

Ensembl | human accession no.

ENSG00000083097

NCBI accession no.

NM_015018

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... DOPEY1(23033) , DOPEY1(23033)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Ian J McGough et al.
Nature communications, 9(1), 3737-3737 (2018-09-15)
Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-retromer assembly for

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