E0270

Ethylenediaminetetraacetic acid tripotassium salt dihydrate

98% (titration)

• Synonym(s): EDTA tripotassium salt, Edathamil, Tripotassium ethylenediaminetetraacetate dihydrate
• Linear Formula: (KOOCCH₂)₂NCH₂CH₂N(CH₂COOK)CH₂COOH · 2H₂O
• CAS Number: 65501-24-8
• Molecular Weight: 442.54
• Beilstein/REAXYS Number: 6762497
• MDL number: MFCD00149672
• UNSPSC Code: 12352116
• PubChem Substance ID: 24894365
• NACRES: NA.31

Properties

• biological source: synthetic
• assay: 98% (titration)
• form: powder
• reaction suitability: reagent type: chelator
• pH: 8-9 (20 °C, 50 g/L)
• mp: 182 °C (dec.) (lit.)
• solubility: 3 M KOH: 160 mg/mL, clear, colorless
• storage temp.: room temp
• SMILES string: [K+].[K+].[K+].[H]O[H].[H]O[H].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.3K.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;2*1H2/q;3*+1;;/p-3
• InChI key: MAPFUJCWRWFQIY-UHFFFAOYSA-K

Description

Application

Ethylenediaminetetraacetic acid tripotassium salt dihydrate has been used to coat conical tubes to collect trunk blood for tissue and plasma samples. It has also been used in tubes to collect blood to perform mixed meal test (MMT).

Used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals

Biochem/physiol Actions

Ethylene diamine tetraacetic acid (EDTA) chelates divalent cations like calcium and magnesium in whole blood. It is usually available as a salt, complexed with either potassium or sodium. It is mostly used during hematological tests of the blood sample. It helps to maintain the cellular morphology to prepare blood smears for microscopic analysis. EDTA is abundantly used in RNA purification methods.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H332,H373
• pcodes: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• target_organs: Respiratory Tract
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves