D7750

2′-Deoxycytidine 5′-monophosphate

Sigma Grade, ≥95.0%

• Synonym(s): Deoxycytidylic acid, dCMP
• Empirical Formula (Hill Notation): C₉H₁₄N₃O₇P
• CAS Number: 1032-65-1
• Molecular Weight: 307.20
• Beilstein/REAXYS Number: 41062
• EC Number: 213-849-9
• MDL number: MFCD00006546
• UNSPSC Code: 41106305
• PubChem Substance ID: 24894158
• NACRES: NA.51

Properties

• biological source: synthetic
• Quality Level: 200
• grade: Sigma Grade
• assay: ≥95.0%
• form: powder
• solubility: 1 M NH₄OH: 50 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2
• InChI: 1S/C9H14N3O7P/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
• InChI key: NCMVOABPESMRCP-SHYZEUOFSA-N

Description

General description

2′-Deoxycytidine 5′-monophosphate is a deoxynucleotide building block via which DNA is made. It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine. It is phosphorylated at carbon C-5′.[1]

Application

2′-Deoxycytidine 5′-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA biosynthesis.

2′-Deoxycytidine 5′-monophosphate has been used in Raman spectroscopic studies to determine its Raman total half bandwidths.[2]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)