All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C34H24O5
Molecular Weight:
512.55
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
Recommended Products
assay
99-102% (NMR)
Quality Level
form
solid
shipped in
wet ice
storage temp.
−20°C
SMILES string
O=C1C=CC2=C(c3ccc(OCc4ccccc4)cc3OC2=C1)c5ccccc5C(=O)OCc6ccccc6
InChI
1S/C34H24O5/c35-25-15-17-29-31(19-25)39-32-20-26(37-21-23-9-3-1-4-10-23)16-18-30(32)33(29)27-13-7-8-14-28(27)34(36)38-22-24-11-5-2-6-12-24/h1-20H,21-22H2
InChI key
YZJGKSLPSGPFEV-UHFFFAOYSA-N
Application
DBF is dealkylated by cytochromes P450 (especially CYP2C8, CYP2C9, CYP2C19, and CYP3A) to form a fluorescein ester. Dibenzylfluorescein was reported to be suitable for in vitro assessment of the initial screening of CYP3A4-
mediated drug interactions. The fluorescent fluorescein product can be quantitated after the addition of base, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection.
mediated drug interactions. The fluorescent fluorescein product can be quantitated after the addition of base, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection.
DBF is dealkylated by cytochromes P450 (especially CYP2C8, CYP2C9, CYP2C19, and CYP3A) to form a fluorescein ester. The fluorescent fluorescein product can be quantitated after the addition of base, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection.
Other Notes
Dibenzylfluorescein is light sensitive and should be protected from direct sunlight or UV sources.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Sheila A Tesh et al.
Regulatory toxicology and pharmacology : RTP, 106, 152-168 (2019-04-27)
Mefentrifluconazole (trade name: Revysol®) is an agrochemical active ingredient from the new sub-class of isopropanol-triazole fungicides, with high selective fungicide activity. A full program of toxicity testing conducted according to OECD guidelines has shown mefentrifluconazole (MFZ) to be non-genotoxic and
Pål Trosvik et al.
Scientific reports, 8(1), 20-20 (2018-01-10)
Human activities can cause habitat degradation that may alter the types and quality of available food resources and thus influence the microbiomes of wild animal populations. Furthermore, seasonal shifts in food availability may cause adaptive responses in the gut microbiome
Francisco Esteves et al.
Frontiers in pharmacology, 11, 299-299 (2020-04-08)
NADPH cytochrome P450 oxidoreductase (CPR) is the obligatory electron supplier that sustains the activity of microsomal cytochrome P450 (CYP) enzymes. The variant nature of the isoform-specific proximal interface of microsomal CYPs indicates that CPR is capable of multiple degenerated interactions
N Soto-Ramírez et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 47(10), 1285-1298 (2017-08-18)
Modes of infant feeding such as direct and indirect breastfeeding, and formula feeding, and their combinations may play a role in child health. The aim was to investigate which feeding patterns in the first 6 months pose risks of eczema/skin allergy
Yuchi Zhang et al.
Journal of separation science, 41(2), 483-492 (2017-11-09)
Ultrafiltration liquid chromatography with mass spectrometry can efficiently and rapidly screen and identify ligands from the seeds of Cicer arietinum for human aromatase. Using this method, we identified 11 major compounds, including organic acids, organic acid glycosides, flavone glycosides, isoflavones
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
