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D6446

Sigma-Aldrich

DOV 216,303

≥98% (HPLC)

Synonym(s):

(±)-1-(3,4-dichlorophenyl)-3-azabicyclo-[3.1.0]hexane hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H11Cl2N · HCl
CAS Number:
Molecular Weight:
264.58
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

$132.00


In StockDetails


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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: ≥10 mg/mL

originator

Merck & Co., Inc., Kenilworth, NJ, U.S.

storage temp.

−20°C

SMILES string

Cl.Clc1ccc(cc1Cl)C23CNCC2C3

InChI

1S/C11H11Cl2N.ClH/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11;/h1-3,8,14H,4-6H2;1H

InChI key

KAGBHVBIOJBGBD-UHFFFAOYSA-N

Biochem/physiol Actions

Serotonin-norepinephrine-dopamine reuptake inhibitor.
Triple reuptake inhibitor (TRI); serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI); IC50 values of ~20, 14, and 78 nM, respectively.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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