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Key Documents

D199

Supelco

Dimethcathinone hydrochloride

Synonym(s):

(±)-2-Dimethylamino-1-phenyl-1-propanone hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H15NO · HCl
CAS Number:
Molecular Weight:
213.70
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:

drug control

USDEA Schedule I; Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

H2O: soluble

format

neat

SMILES string

Cl.CC(N(C)C)C(=O)c1ccccc1

InChI

1S/C11H15NO.ClH/c1-9(12(2)3)11(13)10-7-5-4-6-8-10;/h4-9H,1-3H3;1H

InChI key

APOWZIQNQJSLKG-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Sympathomimetic CNS stimulant; exhibits amphetamine-like effects.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S L Markantonis et al.
The Journal of pharmacy and pharmacology, 38(7), 515-519 (1986-07-01)
The absorption of diethylpropion (DEP I), dimethylpropion (DMP I) and some of their basic metabolites into and passage through the skin was investigated and a comparison of their metabolism following oral and percutaneous administration made. High percentages (60-80%) of DEP
S L Markantonis et al.
Biochemical medicine and metabolic biology, 42(1), 1-8 (1989-08-01)
A study of the in vitro metabolism of dimethylpropion using different tissue homogenates of certain animals showed that: 1. Only the two major metabolites of dimethylpropion, i.e., methylpseudoephedrine and monomethylpropion were formed. 2. Species variation was observed with regard to
M Pokrajac et al.
Rapid communications in mass spectrometry : RCM, 5(2), 59-61 (1991-02-01)
Complex metabolic mixtures of 2-aminopropiophenones, obtained both after in vitro and human in vivo metabolism of these compounds, have been investigated using both mass spectrometry and gas chromatography/mass spectrometry. The mass spectrometric fragmentation schemes of the compounds have been proposed
W E Soholing
Fortschritte der Medizin, 100(7), 289-293 (1982-02-18)
We treated 30 patients between 22 to 30 years of age, who showed static labile circulatory disturbances of blood pressure. We carried out a double blind study following a two week schedule using for treatment an "indirect" sympathomimeticum Dimepropion-HCI. Control
The stereoselective metabolism of dimethylpropion and monomethylpropion.
S L Markantonis et al.
Biochemical pharmacology, 35(3), 529-532 (1986-02-01)

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