U937 Cell Line human

85011440, human lung (lymphoblast), Lymphoblast

• Synonym(s): U-937 Cells
• UNSPSC Code: 41106514

Properties

• product name: U937 Cell Line human, from human lung(lymphoblast), 85011440
• biological source: human lung (lymphoblast)
• growth mode: Suspension
• karyotype: Not specified
• morphology: Lymphoblast
• products: Not specified
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• shipped in: dry ice
• storage temp.: −196°C

Description

Cell Line Origin

Human Caucasian histiocytic lymphoma

Cell Line Description

Derived from malignant cells of a pleural effusion of 37 year old caucasian male with diffuse histiocytic lymphoma. One of only a few human lines still expressing many of the monocytic like characteristics exhibited by cells of histiocytic origin.

Application

Tumourigenicity studies

U937 Cell Line human has been used to study the toxicity of propolis extracts against U937 cells and to study the uptake of apoptotic bodies (derived from monocytic U-937 cells) by primary meningothelial cells (PMECs).

DNA Profile

STR-PCR Data: Amelogenin: X
CSF1PO: 12
D13S317: 10,12
D16S539: 12
D5S818: 12
D7S820: 9,11
THO1: 6,9.3
TPOX: 8,11
vWA: 14,15

Culture Medium

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Subculture Routine

Maintain cultures between 2-9x100,000 cells/ml; 5% CO₂; 37°C. Cells may take up to 72 hours until confluent.

Other Notes

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