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Key Documents

C5982

Sigma-Aldrich

7-Chloro-4-hydroxy-2-phenyl-1,8-naphthyridine

solid

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About This Item

Empirical Formula (Hill Notation):
C14H9N2OCl
Molecular Weight:
256.69
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

form

solid

color

white

solubility

DMSO: 6 mg/mL
H2O: insoluble

SMILES string

Oc1cc(nc2nc(Cl)ccc12)-c3ccccc3

Gene Information

Biochem/physiol Actions

A1 adenosine receptor antagonist.

Packaging

Store tightly sealed.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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P L Ferrarini et al.
Journal of medicinal chemistry, 43(15), 2814-2823 (2000-08-24)
A series of 1,8-naphthyridine derivatives (12-36), bearing a phenyl group in position 2 and various substituents in positions 4 and 7, were synthesized in an attempt to obtain potent, selective antagonists for the A1 adenosine receptor subtype. The compounds were

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