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About This Item
Empirical Formula (Hill Notation):
C16H19N3O8SZn
CAS Number:
Molecular Weight:
478.79
EC Number:
MDL number:
UNSPSC Code:
51101500
PubChem Substance ID:
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mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[H][C@]12SCC(COC(C)=O)=C3N1C(=O)[C@H]2NC(=O)CCC[C@H](N)C(=O)O[Zn]OC3=O
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General description
Chemical structure: ß-lactam
Application
Cephalosporin C zinc salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis.
Cephalosporin C zinc salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. Cephalosporin C has been used to determine activity during stopped-flow Fuorescence spectrometric measurements of association . It is also used as a substrate to detect Cephalosporinase activity .
Biochem/physiol Actions
Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.
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Jihong Wang et al.
The Journal of biological chemistry, 284(1), 595-609 (2008-10-09)
In a previous study, we examined thermodynamic parameters for 20 alanine mutants in beta-lactamase inhibitory protein (BLIP) for binding to TEM-1 beta-lactamase. Here we have determined the structures of two thermodynamically distinctive complexes of BLIP mutants with TEM-1 beta-lactamase. The
Heritable mass conversion of a mutant penicillinase-negative culture of Bacillus cereus to a positive fully de-repressed state.
M R Pollock et al.
Journal of general microbiology, 59(3), 303-316 (1969-12-01)
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