C1788

(±)-Catechin hydrate

• Synonym(s): trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, trans-3,3′,4′,5,7-Pentahydroxyflavane
• Empirical Formula (Hill Notation): C₁₅H₁₄O₆ · xH₂O
• CAS Number: 7295-85-4
• Molecular Weight: 290.27 (anhydrous basis)
• Beilstein/REAXYS Number: 92762
• EC Number: 230-731-2
• MDL number: MFCD00149354
• UNSPSC Code: 85151701
• PubChem Substance ID: 57653989
• NACRES: NA.79

Properties

• assay: ≥96% (HPLC)
• form: powder
• technique(s): HPLC: suitable
• color: white to light brown
• mp: 200 °C (decomposes on heating)
• storage temp.: 2-8°C
• SMILES string: [H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3
• InChI: 1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
• InChI key: OFUMQWOJBVNKLR-NQQJLSKUSA-N

Description

General description

Catechin is produced by Cutch tree and is abundantly found in tea leaves, grape seeds, vegetables and plant-based beverages. It is a plant-derived, polyphenolic anti-oxidant and acts as a plant secondary metabolite.

Application

(±)-Catechin hydrate has been used:

• to study its modulatory effect on drug resistance in human ovarian cancer cells
• to construct the standard curve of total flavonoid content
• to study its effects on the physiological parameters of Solanum lycopersicum

Biochem/physiol Actions

Catechin has phytotoxic properties. Racemic catechin may be used in studies on seed germination and plant invasiveness. Catechin and Epigallocatechin gallate (EGCG) may be used with other polyphenol flavonoids to study their effects in oxidation and peroxidation-related processes.

Polyphenolic antioxidant. Used in traditional Chinese medicine.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves