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C0250

Sigma-Aldrich

Sodium cacodylate trihydrate

≥98%

Synonym(s):

Cacodylic acid sodium salt trihydrate, Dimethylarsinic acid sodium salt, Dimethylarsonic acid sodium salt

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$65.20
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$114.00
100 G
$281.00
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$1,090.00

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10 G
$65.20
25 G
$114.00
100 G
$281.00
500 G
$1,090.00

About This Item

Linear Formula:
(CH3)2AsO2Na · 3H2O
CAS Number:
6131-99-3
Molecular Weight:
214.03
Beilstein/REAXYS Number:
3702348
EC Number:
204-708-2
MDL number:
MFCD00149079
UNSPSC Code:
12161700
PubChem Substance ID:
24892242
NACRES:
NA.21

$65.20

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Quality Level

200

assay

≥98%

form

powder

pH

5.1-7.4

pKa (25 °C)

6.27

solubility

water: 100 mg/mL, clear, colorless

application(s)

ADME/TOX

storage temp.

room temp

SMILES string

[Na+].[H]O[H].[H]O[H].[H]O[H].C[As](C)([O-])=O

InChI

1S/C2H7AsO2.Na.3H2O/c1-3(2,4)5;;;;/h1-2H3,(H,4,5);;3*1H2/q;+1;;;/p-1

InChI key

RLGWPHBPRCROJO-UHFFFAOYSA-M

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General description

Sodium cacodylate is an organic arsenic compound that is metabolized to produce inorganic, trivalent arsenic in vivo. Sodium cacodylate has been used as a source of arsenic in toxicological research.[1] It is used as a buffer with an effective pH buffering range of 5.1-7.4. In microscopy studies, the buffering capacity of cacodylate prevents excess acidity that may result from tissue fixation.[2][3]

Application

Sodium cacodylate trihydrate has been used in the stabilization of the fixatives for electron microscopy.[4] It has also been used to collect vibratome sections to perform nucleoside-diphosphatase technique.[5]

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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

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Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8961
BCCK3780
BCCH7696
BCCG7114
SLCC5876

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Subcellular adaptation of the human diaphragm in chronic obstructive pulmonary disease
Orozco LM, et al.
The European Respiratory Journal, 13(2), 371-378 (1999)
Imaging myelinated nerve fibres by confocal fluorescence microscopy: individual fibres in whole nerve trunks traced through multiple consecutive internodes
Reynolds RJ, et al.
Journal of Neurocytology, 23(9), 555-564 (1994)
A pre-embedding technique for immunocytochemical visualization of cathepsin D in cultured cells subjected to oxidative stress
Roberg K and Ollinger K
The Journal of Histochemistry and Cytochemistry, 46(3), 411-418 (1998)
Cytotoxic effect of three arsenic compounds in HeLa human tumor and bacterial cells
Abdullaev F, et al.
Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 493(1), 31-38 (2001)
Tania Limongi et al.
Frontiers in bioengineering and biotechnology, 8, 84-84 (2020-03-03)
Polycaprolactone (PCL) is a biocompatible and biodegradable polymer widely used for the realization of 3D scaffold for tissue engineering applications. The hot embossing technique (HE) allows the obtainment of PCL scaffolds with a regular array of micro pillars on their
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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