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B5763

Sigma-Aldrich

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

Synonym(s):

MTBSTFA

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About This Item

Linear Formula:
CF3CON(CH3)Si(CH3)2C(CH3)3
CAS Number:
77377-52-7
Molecular Weight:
241.33
Beilstein/REAXYS Number:
3606546
MDL number:
MFCD00009671
UNSPSC Code:
12352000

refractive index

n20/D 1.402 (lit.)

bp

172-175 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

InChI

1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

InChI key

QRKUHYFDBWGLHJ-UHFFFAOYSA-N

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Application

Useful silylating reagent, less moisture sensitive than others.

replaced by

Product No.
Description
Pricing

pictograms

Flame
GHS02

signalword

Warning

hcodes

H226

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

113.0 °F - closed cup

flash_point_c

45 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

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Xiaowei Wang et al.
Journal of chromatography. A, 1216(35), 6267-6273 (2009-07-31)
A sample pretreatment method for the determination of 18 chlorophenols (CPs) in aqueous samples by derivatization liquid-phase microextraction (LPME) was investigated using gas chromatography-mass spectrometry. Derivatization reagent was spiked into the extraction solvent to combine derivatization and extraction into one
R Montes et al.
Journal of chromatography. A, 1216(2), 205-210 (2008-12-17)
A fast and novel sample preparation procedure for the determination of triclosan (TCS) and methyltriclosan (MTCS) in water samples is presented. Dispersive liquid-liquid microextraction, using a ternary mixture consisting of a disperser, an extractant and N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide (MTBSTFA) as derivatization reagent
Martin Adiels et al.
Rapid communications in mass spectrometry : RCM, 24(5), 586-592 (2010-02-09)
Stable isotope kinetic studies play an important role in the study of very-low density lipoprotein (VLDL) metabolism, including basic and clinical research. Today, [1,1,2,3,3-(2)H(5)]glycerol is the most cost-effective alternative to measure glycerol and triglyceride kinetics. Recycling of glycerol from glycolysis
Stephane Morville et al.
Journal of environmental monitoring : JEM, 6(12), 963-966 (2004-11-30)
A method using GC-MS and derivatization with N-(t-butyldimethylsilyl)-N-methyltrifluoroacetamide (MTBSTFA) was developed for the analysis of 20 phenolic compounds in atmospheric samples (gas and particles). Air sampling was carried out using a Hi-Vol sampler with glass fibre filter and XAD-2 resin
Isaac Ohsawa et al.
Journal of chromatography. A, 1122(1-2), 242-248 (2006-05-19)
A method for determining N-ethyldiethanolamine (EDEA), N-methyldiethanolamine (MDEA) and triethanolamine (TEA), hydrolysis products of nitrogen mustards, in water, urine and blood samples using gas chromatography-mass spectrometry (GC-MS) after derivatization by tert-butyldimethylsilylation (TBDMS) is described. The sample solution was evaporated to
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