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Key Documents

B5667

Sigma-Aldrich

5-Bromo-6-chloro-3-indolyl phosphate p-toluidine salt

~97% (HPLC)

Synonym(s):

Magenta phosphate

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About This Item

Empirical Formula (Hill Notation):
C8H6BrClNO4P · C7H9N
CAS Number:
Molecular Weight:
433.62
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

assay

~97% (HPLC)

Quality Level

form

powder

solubility

DMF: 50 mg/mL, clear, orange

storage temp.

−20°C

SMILES string

Cc1ccc(N)cc1.OP(O)(=O)Oc2c[nH]c3cc(Cl)c(Br)cc23

InChI

1S/C8H6BrClNO4P.C7H9N/c9-5-1-4-7(2-6(5)10)11-3-8(4)15-16(12,13)14;1-6-2-4-7(8)5-3-6/h1-3,11H,(H2,12,13,14);2-5H,8H2,1H3

InChI key

WUHVYTJTZAKPOS-UHFFFAOYSA-N

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Legal Information

Magenta is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Dorota Rybaczek et al.
Histochemistry and cell biology, 135(3), 263-280 (2011-02-25)
Here, we demonstrate that in HeLa cells, Ser317 of Chk1 undergoes phosphorylation in response to replication stress induced by hydroxyurea. We also demonstrate the existence of constitutive (interphase and mitotic) Chk1 kinase phosphorylation, the translocation of its phosphorylated form from

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