B0309

Bacteriorhodopsin from Halobacterium salinarum

D96N Mutant

• CAS Number: 53026-44-1
• MDL number: MFCD00130599
• UNSPSC Code: 12352202

Properties

• biological source: Halobacterium salinarium
• form: lyophilized powder
• technique(s): ligand binding assay: suitable
• UniProt accession no.: B0R5N9
• storage temp.: 2-8°C
• Gene Information: Halobacterium salinarium ... OE_RS05715(5953595) , VNG_RS05715(144807)

Description

General description

Bacteriorhodopsin is the prototypical "seven-helix" transmembrane protein (with seven α-helical domains), whose study led to advances in understanding G protein-coupled receptors (GPCRs). In Halobacteria, it acts as a light-harvesting protein, producing a proton gradient across the cell wall that is then used to drive biosynthetic processes.

Application

Bacteriorhodopsin is of interest in the development of artificial retinas, optical associative processors, and three-dimensional memory storage devices.

The mutant D96N is useful for a wide range of data-storage and information processing applications, due the extended relaxation time.

Biochem/physiol Actions

A transmembrane retinylidine protein that functions as a proton pump driven by light energy in Holobacterium.

Physical form

Isolated from Halobacterium salinarum sp. L33 as Purple Membranes

Preparation Note

Aqueous suspensions may be sonicated to achieve the desired homogeneity and may be stored for a short time at a temperature of 2-8 °C or at a temperature of -20 °C without time limitation.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)