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AV54369

Sigma-Aldrich

Anti-NKIRAS2 (AB1) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-DKFZP434N1526, Anti-KBRAS2, Anti-KappaB-Ras2, Anti-MGC74742, Anti-NFKB inhibitor interacting Ras-like 2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

21 kDa

species reactivity

rabbit, bovine, mouse, horse, pig, human, rat, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_060065

UniProt accession no.

Q9NYR9

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... NKIRAS2(28511)

Immunogen

Synthetic peptide directed towards the middle region of human NKIRAS2

Application

Anti-NKIRAS2 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

Biochem/physiol Actions

NKIRAS2 (NFKB inhibitor interacting Ras-like 2) encodes a protein that belongs to Ras family and κB-Ras subfamily. NKIRAS2 interacts with PEST domains of IκBα and IκBβ [inhibitors of the transcription factor nuclear factor κ B (NF-κB)] and decreases their rate of degradation.

Sequence

Synthetic peptide located within the following region: KKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLE

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C Fenwick et al.
Science (New York, N.Y.), 287(5454), 869-873 (2000-02-05)
Small guanosine triphosphatases, typified by the mammalian Ras proteins, play major roles in the regulation of numerous cellular pathways. A subclass of evolutionarily conserved Ras-like proteins was identified, members of which differ from other Ras proteins in containing amino acids

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