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Aqueous solutions of cysteine oxidize to cystine on contact with air at neutral or alkaline pH. We recommend making aqueous solutions fresh. NAC is relatively stable in acid. Solutions in acid are stable and can be stored at -20 °C.
A9165
N-Acetyl-L-cysteine
N-Acetyl-L-cysteine
≥99% (TLC), suitable for cell culture, BioReagent
Synonym(s):
LNAC, NAC
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5 G
$38.20
25 G
$102.00
100 G
$327.00
About This Item
Linear Formula:
HSCH2CH(NHCOCH3)CO2H
CAS Number:
Molecular Weight:
163.19
Beilstein/REAXYS Number:
1724426
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
Product Name
N-Acetyl-L-cysteine, BioReagent, suitable for cell culture
product line
BioReagent
Quality Level
assay
≥99% (TLC)
form
powder
technique(s)
cell culture | mammalian: suitable
color
white to off-white
mp
106-108 °C (lit.)
solubility
H2O: 100 mg/mL (with heating)
storage temp.
2-8°C
SMILES string
CC(=O)N[C@@H](CS)C(O)=O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChI key
PWKSKIMOESPYIA-BYPYZUCNSA-N
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Application
Biochem/physiol Actions
Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.
Application
Product No.
Description
Pricing
also commonly purchased with this product
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Description
Pricing
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Chromatograms
application for HPLC-
How stable is a solution of Product A9165, N-acetyl cysteine (NAC)?
1 answer-
Helpful?
-
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What is the half life of Product A9165, N-Acetyl-L-cysteine (NAC), in cell culture?
1 answer-
We have not tested the half-life of NAC solutions in our labs here at Sigma. However, this subject has been reviewed in Neuropsychopharmacology, 29, 2018-2023 (2004).
Helpful?
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