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A8427

Sigma-Aldrich

Antipyrylazo III

suitable for determination of calcium (per Anal. Chim. Acta, 71, 343 (1974)), ~95%

Synonym(s):

3,6-Bis(4-antipyrylazo)-4,5-dihydroxy-2,7-naphthalenedisulfonic acid disodium salt

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About This Item

Empirical Formula (Hill Notation):
C32H26N8Na2O10S2
CAS Number:
14918-39-9
Molecular Weight:
792.71
Beilstein/REAXYS Number:
956469
EC Number:
238-988-2
MDL number:
MFCD00042700
UNSPSC Code:
12352204

assay

~95%

suitability

suitable for determination of calcium (per Anal. Chim. Acta, 71, 343 (1974))

SMILES string

[Na+].[Na+].CN1N(c2ccccc2)C(=O)C(\N=N\c3c(O)c4c(O)c(\N=N\C5=C(C)N(C)N(c6ccccc6)C5=O)c(cc4cc3S([O-])(=O)=O)S([O-])(=O)=O)=C1C

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Linkage

Similar to A 5894, but produced by Sigma.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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M Irving et al.
The Journal of general physiology, 93(4), 585-608 (1989-04-01)
Antipyrylazo III was introduced into frog cut twitch fibers (17-19 degrees C) by diffusion. After action potential stimulation, the change in indicator absorbance could be resolved into two components that had different time courses and wavelength dependences. The first component
C E Gavin et al.
Analytical biochemistry, 192(1), 44-48 (1991-01-01)
The metallochromic indicator antipyrylazo III can be used for the rapid and convenient monitoring of Mn2+ transport in biological systems. The apparent KD of the Mn-antipyrylazo III complex in buffered 150 mM KCl (pH 7.2 at 20 degrees C) is
Luba Ginzburg et al.
Journal of neurochemistry, 104(1), 140-146 (2008-01-05)
We previously observed that gangliosides GM2, GM1, and GM3 inhibit Ca2+-uptake via the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) in neurons and in brain microsomes. We now systematically examine the effect of various gangliosides and their analogs on Ca2+-uptake via SERCA and
D Feldmeyer et al.
The Journal of physiology, 421, 343-362 (1990-02-01)
1. Intramembrane charge movements and changes in intracellular Ca2+ concentration were studied in voltage clamp experiments on cut twitch muscle fibres of the frog. The restoration from inactivation caused by steady depolarization and its modification by the phenylalkylamine Ca2+ channel
A Struk et al.
Cell calcium, 23(1), 23-32 (1998-05-07)
Fura-2 is one of the most frequently used fluorescent Ca indicator dyes; yet it has limitations in tracking large intracellular Ca transients due to its high affinity for Ca. Since high affinity is of advantage when small Ca changes are
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