This recombinant protein contains 584 amino acid residues (66,357 Dalton) derived from the prototypical human serum albumin sequence, Gene Bank Accession No. M12523, with a single deletion of the N-terminal residue (Asp). The N-terminal deletion of the Asp reduces the affinity by which nickel and copper bind to the protein. Otherwise, the biological properties are identical as for the full-length protein.
A7223
Albumin human
recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)
Synonym(s):
Albagen™, rHSA
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1 G
$608.00
About This Item
Empirical Formula (Hill Notation):
C2936H4624N786O889S41
CAS Number:
Molecular Weight:
66471.53
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.25
Recommended Products
biological source
human
Quality Level
recombinant
expressed in Pichia pastoris
assay
≥90% (SDS-PAGE)
form
solution
mol wt
monomer ~67 kDa
concentration
5% in aqueous buffer
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Gene Information
human ... ALB(213)
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application
This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.
Biochem/physiol Actions
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Physical properties
Recombinant construct with N-terminal deletion of Asp. Structurally equivalent to native albumin by x-ray crystallography. The N-terminal Asp is the principal Cu2+ and Ni2+ chelation site; its deletion eliminates an important antigenic determinant, and the protein is hypoallergenic. Also blocked at Cys34 to improve stability, monomer content and homogeneity.
Physical form
Solution in phosphate buffered saline containing 4 mM sodium caprylate and 4 mM N-acetyltryptophan.
Other Notes
View more information on human serum albumin.
Legal Information
Albagen is a trademark of Albumin Therapeutics, LLC.
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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What is the molecular mass of the recombinant albumin used in preparing Product A7223, Albumin human - recombinant?
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How many milliliters are in the 1 gram package size of Product A7223, Albumin human - recombinant?
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There are 20 mL of albumin solution in the 1 gram package size.
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What is the concentration of Product A7223, Albumin human - recombinant?
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The concentration of this solution is 50 mg/mL.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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