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Key Documents

A2727

Sigma-Aldrich

N-Acetyl-Adhesin Amide Fragment 1025-1044

≥95% (HPLC)

Synonym(s):

p1025

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About This Item

Empirical Formula (Hill Notation):
C97H160N26O32
Molecular Weight:
2202.46
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.26

Quality Level

assay

≥95% (HPLC)

form

solid

storage temp.

−20°C

Amino Acid Sequence

Ac-Gln-Leu-Lys-Thr-Ala-Asp-Leu-Pro-Ala-Gly-Arg-Asp-Glu-Thr-Thr-Ser-Phe-Val-Leu-Val-NH2

Biochem/physiol Actions

Antimicrobial peptide that has been shown to specifically inhibit binding of a cell surface adhesion of Streptococcus mutans, the main etiological agent of dental caries, to salivary receptors in vitro.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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C G Kelly et al.
Nature biotechnology, 17(1), 42-47 (1999-01-27)
The earliest step in microbial infection is adherence by specific microbial adhesins to the mucosa of the oro-intestinal, nasorespiratory, or genitourinary tract. We inhibited binding of a cell surface adhesin of Streptococcus mutans to salivary receptors in vitro, as measured

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