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88276

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 3,350

Synonym(s):

Polyethylene glycol, Polyethylene oxide, Polyoxyethylene, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.26

product line

BioUltra

form

powder

mol wt

Mr 3000-3700

impurities

insoluble matters, passes filter test

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL, clear, colorless

anion traces

chloride (Cl-): <50 mg/kg
sulfate (SO42-): <50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) (PEG) is a linear polyether of ethylene glycol (ethane-1,2-diol). It is soluble in water, benzene, ethanol, acetonitrile, and dichloromethane. However, it is insoluble in diethyl ether and hexane. This non-ionic polymer can exist in the monomer and aqueous phases.

Application

Poly(ethylene glycol) has been used:

  • to grow the crystals of HLA-A∗02:01-N222-230 LLLDRLNQL (pHLA) complex
  • in the fabrication of ultrathin, free-standing, and porous polymer membranes for retinal tissue engineering
  • to grow the crystals of the C2c2-crRNA complex
  • to grow the crystals of the apo-C2c2 thermolysin-resistant core

Biochem/physiol Actions

Poly(ethylene glycol) (PEG) is used in several pharmaceutical applications. This polymer occurs as a preservative and is used in biomedical applications like drug delivery systems, biosensing, and tissue engineering. PEG is also used in cosmetic ointments and creams. It is used as a binding and dispersing agent in chemical and other industries.

Features and Benefits

  • Environment friendly
  • Biocompatible
  • Unique solvent solution

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Polymers and polymeric hybrids for targeted drug delivery
Islam R and Fang J
Journal of Separation Science, 303-322 (2022)
Polymers for 3D bioprinting
Beata K
Journal of Separation Science, 337-349 (2022)
Novel method for the fabrication of ultrathin, free-standing and porous polymer membranes for retinal tissue engineering
Tan EYS, et al.
Journal of materials chemistry. B, 5(28), 5616-5622 (2017)
Liang Liu et al.
Cell, 168(1-2), 121-134 (2017-01-14)
C2c2, the effector of type VI CRISPR-Cas systems, has two RNase activities-one for cutting its RNA target and the other for processing the CRISPR RNA (crRNA). Here, we report the structures of Leptotrichia shahii C2c2 in its crRNA-free and crRNA-bound
Application of compatibilized polymer blends in biomedical fields
Zarrintaj P, et al.
Journal of Separation Science, 511-537 (2020)

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