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68373

Sigma-Aldrich

Visfatin human, recombinant from E. coli

≥90% (GE)

Synonym(s):

PBEF, Pre-B cell colony-enhancing factor

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.77

assay

≥90% (GE)

form

solid

technique(s)

western blot: suitable

impurities

≤0.1 EU/μg protein endotoxin

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... NAMPT(10135)

General description

Visfatin, also known as pre-B cell colony-enhancing factor, is a cytokine that is highly expressed in visceral fat and was originally isolated as a secreted factor that synergizes with IL-7 and stem cell factors to promote the growth of B cell precursors

Application

Western blotting

Analysis Note

Endotoxin: <0.1 EU/μg protein (LAL test)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Miao-Pei Chen et al.
The Journal of clinical endocrinology and metabolism, 91(1), 295-299 (2005-10-20)
Visfatin (also known as pre-B cell colony-enhancing factor or PBEF) is a cytokine that is highly expressed in visceral fat and whose blood levels correlate with obesity. Originally isolated as a secreted factor that promotes the growth of B cell
Janin Berndt et al.
Diabetes, 54(10), 2911-2916 (2005-09-28)
Visceral and subcutaneous adipose tissue display important metabolic differences that underlie the association of visceral obesity with obesity-related cardiovascular and metabolic alterations. Recently, visfatin was identified as an adipokine, which is predominantly secreted from visceral adipose tissue both in humans
Mélodie Diot et al.
Reproduction (Cambridge, England), 150(1), 53-63 (2015-04-29)
In mammals, nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine produced by adipose tissue that is found in intracellular and extracellular compartments. The intracellular form of NAMPT is a nicotinamide phosphoribosyltransferase, whereas the extracellular form is considered an adipokine. In humans, NAMPT
Drew J Adams et al.
ACS chemical biology, 9(10), 2247-2254 (2014-07-25)
The small-molecule probes STF-31 and its analogue compound 146 were discovered while searching for compounds that kill VHL-deficient renal cell carcinoma cell lines selectively and have been reported to act via direct inhibition of the glucose transporter GLUT1. We profiled
Gong Cheng et al.
Oncology reports, 34(2), 987-994 (2015-06-13)
Visfatin is considered to be a biomarker in various types of cancers. However, no evidence has been reported for the direct effect of visfatin on osteosarcoma cell metastasis. The aims of the present study were to investigate the influence of

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