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Sigma-Aldrich

Hemoglobin from bovine blood

≥85% (HPCE)

Synonym(s):

Bovine hemoglobin, Hb, Methemoglobin

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About This Item

CAS Number:
9008-02-0
MDL number:
MFCD00131282
UNSPSC Code:
12352202
eCl@ss:
42030116

biological source

bovine blood

assay

≥85% (HPCE)
~95% protein basis

mol wt

Mr ~64500

loss

≤5% loss on drying

UniProt accession no.

P01966
P02070
P02081
P06642
P06643

storage temp.

2-8°C

Gene Information

cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)

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Application

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Toru Yamada et al.
PloS one, 7(11), e50271-e50271 (2012-11-28)
In conventional functional near-infrared spectroscopy (fNIRS), systemic physiological fluctuations evoked by a body's motion and psychophysiological changes often contaminate fNIRS signals. We propose a novel method for separating functional and systemic signals based on their hemodynamic differences. Considering their physiological
N F Schreiter et al.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 185(4), 358-366 (2013-03-16)
To investigate whether changes in hemodynamics induced by Valsalva maneuver can be exploited for detecting and characterizing breast lesions by optical mammography. 30 women underwent optical imaging of the breast using a DYNOT 232 system and performing Valsalva maneuvers prior
Konstantinos Balaskas et al.
The British journal of ophthalmology, 97(5), 558-560 (2012-11-10)
This study examines the differences in spectral absorption properties between the maculae of patients with active neovascular macular degeneration and those with early age related maculopathy (ARM). Patients attending for management of neovascular age related macular degeneration (AMD) underwent multispectral
Omar Falou et al.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2012, 3155-3158 (2013-02-01)
The necessity for a non-invasive and inexpensive imaging modality to both diagnose and monitor treatment response has lead to renewed interest in the potential of optical imaging. The aim of this study was to investigate the potential of diffuse optical
R Bokiniec et al.
Advances in medical sciences, 57(2), 348-355 (2012-11-20)
The aim of this study was to determine brain oxygenation in full-term and preterm neonates using near infrared spectroscopy. A total of 88 full-term and preterm newborn infants without hypoxic-ischaemic disorders admitted to the NICU were examined using NIRS on
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Chromatograms

application for HPLC

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