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205M-1

Sigma-Aldrich

CD5 (4C7) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

4C7, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (205M-14)
vial of 0.5 mL concentrate (205M-15)
bottle of 1.0 mL predilute (205M-17)
vial of 1.0 mL concentrate (205M-16)
bottle of 7.0 mL predilute (205M-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50

isotype

IgGκ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD5(921)

Related Categories

General description

CD5 is a T-cell marker that also reacts with a range of neoplastic B-cells, e.g. B-cell chronic lymphocytic leukemia (B-CLL), B-cell small lymphocytic lymphoma (B-SLL), and mantle cell lymphoma. CD5 is expressed in T lymphocyte subsets and is modulated during cellular activation. CD5 does not react with granulocytes or monocytes.

Linkage

CD5 Positive Control Slides, Product No. 205S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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CD5+ B lymphocytes.
M T Kasaian et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 197(3), 226-241 (1991-07-01)
Ben Hatano et al.
Pathology international, 52(5-6), 400-405 (2002-07-09)
Peripheral T-cell lymphomas (PTCL) with nodular growth patterns are very rare, with only 17 cases reported previously. Here, we report a case of PTCL with a nodular growth pattern. The patient was an 81-year-old Japanese woman who complained of malaise
Chung-Che Chang et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 15(10), 1051-1057 (2002-10-16)
CD5 expression in neoplastic large B-cells in T-cell/histiocyte-rich large B-cell lymphoma has not been reported, to the best of our knowledge. Here we describe the first case of CD5+ T-cell/histiocyte-rich large B-cell lymphoma that is well documented by histomorphology, immunohistochemistry
S H Tan et al.
The British journal of dermatology, 149(3), 542-553 (2003-09-27)
Cutaneous lymphomas other than mycosis fungoides (MF) are a heterogeneous group with wide variations in clinical presentation, biological behaviour and prognosis. New classification systems have been designed or proposed in recent years, with well-defined disease entities and emphasis on the
J K Chan et al.
Histopathology, 25(6), 517-536 (1994-12-01)
A new classification of lymphoid neoplasms, mostly based on existing terminology, is proposed by the International Lymphoma Study Group. The proposed classification was reached through a consensus of the members, despite their diverse backgrounds, and consists of a listing of
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