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08340

Sigma-Aldrich

5-Aminolevulinic acid hydrochloride

≥97.0% (AT)

Synonym(s):

δ-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, 5-Aminolaevulinic acid hydrochloride, ALA

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About This Item

Linear Formula:
NH2CH2C(O)CH2CH2COOH · HCl
CAS Number:
5451-09-2
Molecular Weight:
167.59
Beilstein/REAXYS Number:
3690651
EC Number:
226-679-5
MDL number:
MFCD00012869
UNSPSC Code:
12352200
PubChem Substance ID:
329748571

assay

≥97.0% (AT)

form

powder or crystals

impurities

≤1% water

color

white to faint beige

mp

~150 °C (dec.)

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
K: ≤100 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤60 mg/kg
Pb: ≤5 mg/kg
Zn: ≤20 mg/kg

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl[H].NCC(=O)CCC(O)=O

InChI

1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H

Inchi Key

ZLHFONARZHCSET-UHFFFAOYSA-N

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Biochem/physiol Actions

Intermediate in heme biosynthesis.

Other Notes

Substrate for the assay of γ-aminolevulinic acid dehydratase[1][2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCBS8506V
BCBS2437V
BCBS0797V
BCBR1121V
BCBQ5574V

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Quantification of neurodegeneration in animal models is typically assessed by time-consuming and observer-dependent immunocytochemistry. This study aimed to investigate if newly developed ELISA techniques could provide an observer-independent, cost-effective and time-saving tool for this purpose. Neurofilament heavy chain (NfH(SM135)), astrocytic
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D Gurne et al.
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