494488

N,N-Dimethylformamide

biotech. grade, ≥99.9%

• Synonym(s): DMF, NSC 5356
• Linear Formula: HCON(CH₃)₂
• CAS Number: 68-12-2
• Molecular Weight: 73.09
• Beilstein/REAXYS Number: 605365
• EC Number: 200-679-5
• MDL number: MFCD00003284
• UNSPSC Code: 12352111
• PubChem Substance ID: 329757455
• NACRES: NA.21

Properties

• grade: biotech. grade
• Quality Level: 200
• vapor density: 2.5 (vs air)
• vapor pressure: 2.7 mmHg ( 20 °C)
• assay: ≥99.9%
• form: liquid
• autoignition temp.: 833 °F
• expl. lim.: 15.2 %
• impurities: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.005% (water); <8 ppm Free amines as dimethylamine
• evapn. residue: <0.0005%
• refractive index: n20/D 1.430 (lit.)
• pH: 7 (20 °C, 200 g/L)
• bp: 153 °C (lit.)
• mp: −61 °C (lit.)
• solubility: water: miscible
• density: 0.944 g/mL (lit.)
• UV absorption: λ: 270 nm A_max: ≤1.0; λ: 275 nm A_max: ≤0.30; λ: 295 nm A_max: ≤0.10; λ: 310 nm A_max: ≤0.05; λ: 340 nm A_max: ≤0.01; λ: 400 nm A_max: ≤0.01
• application(s): peptide synthesis
• storage temp.: room temp
• SMILES string: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• InChI key: ZMXDDKWLCZADIW-UHFFFAOYSA-N

Description

General description

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Application

N,N-dimethylformamide (DMF) has been used for the preparation of tetraformylcavitand precursor for generating octahedral nanocontainer.

Solvent for many hydrophobic organic compounds.

Packaging

View returnable container options.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H226,H312 + H332,H319,H360D
• pcodes: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 135.5 °F - closed cup
• flash_point_c: 57.5 °C - closed cup