S1304

Sodium acetate trihydrate

meets USP testing specifications

• Synonym(s): Acetic acid sodium salt trihydrate
• Linear Formula: CH₃COONa · 3H₂O
• CAS Number: 6131-90-4
• Molecular Weight: 136.08
• Beilstein/REAXYS Number: 3732037
• EC Number: 204-823-8
• MDL number: MFCD00071557
• UNSPSC Code: 12352300
• PubChem Substance ID: 24899472
• NACRES: NA.21

Properties

• agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• assay: 99.0-101.0% dry basis (HClO₄ , titration)
• form: crystalline
• autoignition temp.: 1112 °F
• pH: 7.5-9.2
• solubility: water: soluble 408 g/L at 20 °C
• application(s): pharmaceutical (small molecule)
• SMILES string: O.O.O.[Na+].CC([O-])=O
• InChI: 1S/C2H4O2.Na.3H2O/c1-2(3)4;;;;/h1H3,(H,3,4);;3*1H2/q;+1;;;/p-1
• InChI key: AYRVGWHSXIMRAB-UHFFFAOYSA-M

Description

Application

• Unraveling the effects of drying techniques on chaya leaves: Metabolomics analysis of nonvolatile and volatile metabolites, umami taste, and antioxidant capacity.: This study explores the impact of different drying methods on the biochemical composition of chaya leaves using sodium acetate trihydrate as a buffer component to measure antioxidant capacity. The research provides insights into optimizing processing methods to retain beneficial compounds and enhance flavor (Hutasingh N et al., 2024).


• The role of urea in formation of the sodium acetate trihydrate (SAT)-urea eutectic liquid: a neutron diffraction and isotopic substitution study.: This paper discusses the use of sodium acetate trihydrate in creating a eutectic mixture with urea, which is characterized by neutron diffraction. The findings highlight the chemical′s utility in studying fluid properties and interactions at the molecular level, useful for designing novel solvents and materials (Byrne EL et al., 2024).


• Fabrication of multi-functional gelatin/deep eutectic solvent/polyacrylonitrile nanofiber membranes via electrospinning.: This research uses sodium acetate trihydrate in the synthesis of advanced nanofiber structures for potential applications in filtration and biotechnology. The study showcases the adaptability of sodium acetate trihydrate in facilitating novel manufacturing processes (Cui Y et al., 2023).


• Preparation, thermal storage properties and application of sodium acetate trihydrate/expanded graphite composite phase change materials.: Highlights the use of sodium acetate trihydrate in developing composite materials for energy storage. This study demonstrates the potential of these composites in enhancing the efficiency of thermal energy systems, which is crucial for developing sustainable energy solutions (Wang KW et al., 2023).


• Improvement and enhancement of oligosaccharide production from Lactobacillus acidophilus using statistical experimental designs and its inhibitory effect on colon cancer.: This paper investigates the role of sodium acetate trihydrate in optimizing the fermentation conditions for the production of bioactive oligosaccharides. The study also examines the anti-cancer properties of these oligosaccharides, providing valuable data for future cancer research and probiotic development (Abo-Zaid GA et al., 2023).

Other Notes

Enzyme substrate for acetate kinase (EC 2.7.2.1)

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)