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M5651

Supelco

Mepenzolate bromide

analytical standard

Synonym(s):

3-Hydroxy-1,1-dimethylpiperidinium bromide benzilate

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About This Item

Linear Formula:
C21H26NO3Br
CAS Number:
76-90-4
Molecular Weight:
420.34
EC Number:
200-992-7
MDL number:
MFCD00079450
UNSPSC Code:
41116107
PubChem Substance ID:
329818020
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Br.C[N]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3

InChI

1S/C21H26NO3.BrH/c1-22(2)15-9-14-19(16-22)25-20(23)21(24,17-10-5-3-6-11-17)18-12-7-4-8-13-18;/h3-8,10-13,19,24H,9,14-16H2,1-2H3;1H

InChI key

FOPUTUUUOOOXQU-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000253441
0000274807
0000286744
097F0944

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R F Ochillo et al.
Research communications in chemical pathology and pharmacology, 36(3), 503-506 (1982-06-01)
The mydriatic effects of mepenzolate, a quarternary antimuscarinic agent, has been investigated and compared with those of atropine by pupillographic analysis in rabbits. The time-response curve for the onset of action for the agents (half-time, ca.5 min) was the same
C S Tsai et al.
Journal of ethnopharmacology, 45(3), 215-222 (1995-03-01)
In our attempt to isolate the pharmacologically active ingredients in the aqueous extracts of Mareya micrantha, we have selected the contractions of the longitudinal muscle of the isolated guinea-pig ileum preparation as a pharmacological marker to monitor retention of pharmacological
M Cohen-Armon et al.
Journal of cardiovascular pharmacology, 6(6), 1148-1155 (1984-11-01)
The possible interaction between the muscarinic receptor and the antiarrythmic drug amiodarone was studied physiologically in the guinea pig ileum, as well as by competition binding experiments in rat brain and cardiac tissues, using the highly specific tritiated muscarinic antagonist
R Reves et al.
Journal of clinical gastroenterology, 5(3), 223-227 (1983-06-01)
Seventy adults in the United States with acute diarrhea who were attending classes in Guadalajara, Mexico, enrolled in a double-blind placebo-controlled treatment study of an anticholinergic drug, mepenzolate bromide (MZB). Thirty-five patients received MZB (50 mg) and 35 received placebo
Y Sudo et al.
Neurology, 51(5), 1297-1302 (1998-11-18)
To investigate the function of the muscarinic cholinergic receptor (mAchR) in narcolepsy and the effects of pharmacotherapy on mAchRs. Muscarinic neural transmission serves as the main executive system in REM sleep. Studies in canine narcolepsy reported an increase in mAchRs
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