BP423

Phytomenadione

British Pharmacopoeia (BP) Reference Standard

• Synonym(s): Vitamin K₁, 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K₁₍₂₀₎
• Empirical Formula (Hill Notation): C₃₁H₄₆O₂
• CAS Number: 84-80-0
• Molecular Weight: 450.70
• Beilstein/REAXYS Number: 2568816
• EC Number: 201-564-2
• MDL number: MFCD00214063
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: phytomenadione
• form: viscous liquid (Clear)
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• refractive index: n20/D 1.527 (lit.)
• mp: −20 °C (lit.)
• density: 0.984 g/mL at 25 °C (lit.)
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
• InChI: 1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
• InChI key: MBWXNTAXLNYFJB-NKFFZRIASA-N

Description

General description

Phytomenadione is a synthetic lipid-soluble forms of vitamin K₁, and works as an essential cofactor for the post-translational γ-carboxyglutamate (Gla) residues in several blood coagulation factors. It is used to treat coagulopathies caused by anticoagulant toxicosis.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phytomenadione BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Phytomenadione Injection

Phytomenadione Tablets

Packaging

Unit quantity: 0.25 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable