BP1075

Mesalazine

British Pharmacopoeia (BP) Reference Standard

• Synonym(s): 5-Aminosalicylic acid, 5-AS, 5-Amino-2-hydroxybenzoic acid, Mesalamine
• Linear Formula: H₂NC₆H₃-2-(OH)CO₂H
• CAS Number: 89-57-6
• Molecular Weight: 153.14
• Beilstein/REAXYS Number: 2090421
• MDL number: MFCD00007877
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: mesalazine, mesalamine
• form: powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• mp: 275-280 °C (dec.) (lit.)
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: Nc1ccc(O)c(c1)C(O)=O
• InChI: 1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
• InChI key: KBOPZPXVLCULAV-UHFFFAOYSA-N
• Gene Information: human ... ALOX5(240) , PPARG(5468) , PTGS1(5742) , PTGS2(5743)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mesalazine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Mesalazine Suppositories

Mesalazine Foam Enema

Mesalazine Enema

Mesalazine Prolonged-release Tablets

Mesalazine Gastro-resistant Tablets

Mesalazine Prolonged-release Granules

5-Aminosalicylic acid is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is brown in color and can be read spectrophotometrically at 450 nm. The reaction may be stopped with 3 N NaOH and read at 550 nm.

Packaging

Unit quantity: 125 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H317,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 536.0 °F
• flash_point_c: 280 °C