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94225

Sigma-Aldrich

Uracil 1-β-D-arabinofuranoside

≥98.0% (HPLC)

Synonym(s):

1-β-D-Arabinofuranosyluracil

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About This Item

Empirical Formula (Hill Notation):
C9H12N2O6
CAS Number:
3083-77-0
Molecular Weight:
244.20
Beilstein/REAXYS Number:
28749
EC Number:
221-386-9
MDL number:
MFCD00065998
UNSPSC Code:
41106305

assay

≥98.0% (HPLC)

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H]([C@@H](O)[C@@H]1O)N2C=CC(=O)NC2=O

InChI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7+,8-/m1/s1

InChI key

DRTQHJPVMGBUCF-CCXZUQQUSA-N

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replaced by

Product No.
Description
Pricing

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Melissa N McCracken et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(5), 1857-1862 (2013-01-16)
Positron emission tomography (PET) reporter genes allow noninvasive whole-body imaging of transplanted cells by detection with radiolabeled probes. We used a human deoxycytidine kinase containing three amino acid substitutions within the active site (hdCK3mut) as a reporter gene in combination
Hyo-Suk Lee et al.
Journal of gastroenterology, 46(3), 410-414 (2010-12-25)
This study was conducted to evaluate the durability of clevudine-induced viral response after the withdrawal of treatment. Patients who showed a complete response [alanine aminotransferase (ALT) normalization and hepatitis B virus (HBV) DNA <4,700 copies/mL for hepatitis B envelope antigen
Jinqing Tang et al.
Frontiers in bioscience (Landmark edition), 17, 569-574 (2011-12-29)
Cytarabine (araC) is a highly active antimetabolite against hematological malignancy while the agent shows limited activity for some patients despite maintenance or continued therapy with ara-C-containing regiments. In this study, we focused to elucidate the mechanism of intrinsic resistance to
Cungang Ding et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 885-886, 97-102 (2012-01-24)
A new, simple and enantioselective normal-phase liquid chromatography-mass spectrometry method was presented for the quantification of clevudine and its enantiomer in human plasma. A C18 cartridge was used in this method to extract the enantiomers in 200μL plasma followed by
Zibo Li et al.
Nuclear medicine and biology, 38(2), 201-206 (2011-02-15)
2'-Deoxy-2'-[(18)F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil ([(18)F]-FMAU) is an established PET probe used to monitor cellular proliferation. For clinical applications, a fully automated cGMP-compliant radiosynthesis would be preferred. However, the current synthesis of [(18)F]-FMAU requires a multistep procedure, making the development of an automated protocol
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