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An NSAID. Circumvents MRP-mediated multidrug resistance. Specifically and significantly potentiates the cytotoxicity of anthracyclines as well as teniposide, VP-16 and vincristine.
Journal of environmental management, 167, 206-213 (2015-12-22)
Mefenamic acid (MEF) is a non-steroidal anti-inflammatory drug indicated for relief of mild to moderate pain, and for the treatment of primary dysmenorrhea. The presence of MEF in raw and sewage waters has been detected worldwide at concentrations exceeding the
International journal of pharmaceutics, 472(1-2), 140-147 (2014-06-15)
The role of surface properties, influenced by particle processing, in particle-particle interactions (powder cohesion) is investigated in this study. Wetting behaviour of mefenamic acid was found to be anisotropic by sessile drop contact angle measurements on macroscopic (>1cm) single crystals
The Cochrane database of systematic reviews, (3)(3), CD007553-CD007553 (2011-03-18)
Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). It is most often used for treating pain of dysmenorrhoea in the short term (seven days or less), as well as mild to moderate pain including headache, dental pain, postoperative and postpartum
Cytochrome P450 BM3 mutants are promising biocatalysts for the production of drug metabolites. In the present study, the ability of cytochrome P450 BM3 mutants to produce oxidative metabolites of structurally related NSAIDs meclofenamic acid, mefenamic acid and tolfenamic acid was
Farmakologiia i toksikologiia, 43(2), 184-186 (1980-03-01)
It is established in in-vitro experiments that mefenamic acid and sodium salicylate inhibit to an equal measure the cell immunity test, a reaction of blast transformation of lymphocytes. The effect increases with the higher concentration of the drugs under study
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