70199

Naphazoline nitrate

tested according to Ph. Eur.

• Synonym(s): Naphazolini nitras, 2-(1-Naphthylmethyl)imidazoline nitrate
• Empirical Formula (Hill Notation): C₁₄H₁₄N₂ · HNO₃
• CAS Number: 5144-52-5
• Molecular Weight: 273.29
• Beilstein/REAXYS Number: 3779329
• EC Number: 225-915-4
• MDL number: MFCD00014316
• UNSPSC Code: 12352200
• PubChem Substance ID: 329762336

Properties

• agency: USP/NF; tested according to Ph. Eur.
• form: crystals
• application(s): pharmaceutical (small molecule)
• SMILES string: O[N+]([O-])=O.C1CN=C(Cc2cccc3ccccc23)N1
• InChI: 1S/C14H14N2.HNO3/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;2-1(3)4/h1-7H,8-10H2,(H,15,16);(H,2,3,4)
• InChI key: ZAHXYMFVNNUHCP-UHFFFAOYSA-N

Description

Application

Therapeutic use to:

• Combat ammonia poisoning
• Treat seasonal allergy rhinitis

Involved in studies on the effects of imidazole drugs on chronotropic and inotropic effects

Pharmacological activity for topical mydriatics and vasoconstrictors

Radioprotector for mice treated with ionizing radiation

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves