68790

Drometrizole trisiloxane

analytical standard

• Synonym(s): 2-(2H-Benzotriazol-2-yl)-4-methyl-6-{2-methyl-3-{1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl}propyl}phenol, Silatrizole
• Empirical Formula (Hill Notation): C₂₄H₃₉N₃O₃Si₃
• CAS Number: 155633-54-8
• Molecular Weight: 501.84
• Beilstein/REAXYS Number: 11343300
• MDL number: MFCD22373626
• UNSPSC Code: 41116107
• PubChem Substance ID: 329760825
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; environmental; food and beverages; personal care
• format: neat
• SMILES string: CC(Cc1cc(C)cc(c1O)-n2nc3ccccc3n2)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C
• InChI: 1S/C24H39N3O3Si3/c1-18-14-20(15-19(2)17-33(9,29-31(3,4)5)30-32(6,7)8)24(28)23(16-18)27-25-21-12-10-11-13-22(21)26-27/h10-14,16,19,28H,15,17H2,1-9H3
• Inchi Key: HUVYTMDMDZRHBN-UHFFFAOYSA-N

Description

General description

Drometrizole trisiloxane (DRT) belongs to the lipophilic benzotriazole derivative class of compounds commonly utilized in sunscreen cosmetics.

Application

DRT may be used as a reference standard for the determination of DRT in:

• Active pharmaceutical ingredients (APIs), formulations and stability samples by reversed phase ultra-high performance liquid chromatography (RP-UPLC) coupled to electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS).
• Suncare formulations by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection.
• Cosmetic products by LC-UV.
• Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure and gas chromatography combined with MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

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Safety Information

• hcodes: H413
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable