49497

Dimethyl sulfate

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• Synonym(s): Sulfuric acid dimethyl ester
• Linear Formula: (CH₃O)₂SO₂
• CAS Number: 77-78-1
• Molecular Weight: 126.13
• Beilstein/REAXYS Number: 635994
• EC Number: 201-058-1
• MDL number: MFCD00008416
• UNSPSC Code: 12000000
• PubChem Substance ID: 329757463
• NACRES: NA.22

Properties

• grade: for GC derivatization
• Quality Level: 100
• vapor density: 4.3 (vs air)
• vapor pressure: 0.7 mmHg ( 25 °C)
• assay: ≥99.0% (GC)
• autoignition temp.: 923 °F
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Alkylations
• technique(s): gas chromatography (GC): suitable
• refractive index: n20/D 1.386 (lit.); n20/D 1.387
• bp: 188 °C (lit.)
• mp: −32 °C (lit.)
• density: 1.333 g/mL at 25 °C (lit.)
• SMILES string: COS(=O)(=O)OC
• InChI: 1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3
• InChI key: VAYGXNSJCAHWJZ-UHFFFAOYSA-N

Description

Application

Dimethyl sulfate may be used as a derivatization reagent for the esterification reaction in the determination of pharmaceuticals by automated aqueous derivatization solid-phase microextraction (SPME) coupled with gas chromatography/mass spectrometry (GC/MS).

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H301,H314,H317,H330,H341,H350
• pcodes: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 181.4 °F - closed cup
• flash_point_c: 83 °C - closed cup