46161

Demeclocycline hydrochloride hydrate

VETRANAL^®, analytical standard

• Synonym(s): Chlorodemethyltetracycline hydrochloride
• Empirical Formula (Hill Notation): C₂₁H₂₁ClN₂O₈ · HCl · xH₂O
• CAS Number: 64-73-3
• Molecular Weight: 501.31 (anhydrous basis)
• Beilstein/REAXYS Number: 5705221
• EC Number: 200-592-2
• MDL number: MFCD00149217
• UNSPSC Code: 41116107
• PubChem Substance ID: 329757091
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: O.Cl.CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O
• InChI: 1S/C21H21ClN2O8.ClH.H2O/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H;1H2/t6-,7-,14-,15-,21-;;/m0../s1
• InChI key: LZJOUJFCRCXBBC-XZJYMHMKSA-N

Description

General description

Chemical structure: tetracycline

Application

Demeclocycline hydrochloride hydrate may be used as an internal standard for the determination of:

• Oxytetracycline and tetracycline in pig manure samples by ultra-high performance liquid chromatography (UHPLC) coupled to triple quadrupole mass spectrometer equipped with electrospray ionization source (QqQ-ESI-MS/MS) and dynamic multiple reaction monitoring (dMRM) mode of detection.
• Oxytetracycline hydrochloride in dairy products by UHPLC-QqQ-ESI-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335,H341
• pcodes: P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves