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45379

Supelco

Chlordecone

PESTANAL®, analytical standard

Synonym(s):

Kepone, Chlordecone, Perchloropentacyclo[5.3.0.02,6.03,9.04,8]decan-5-one

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About This Item

Empirical Formula (Hill Notation):
C10Cl10O
CAS Number:
Molecular Weight:
490.64
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

ClC1(Cl)C2(Cl)C3(Cl)C4(Cl)C(=O)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl

InChI

1S/C10Cl10O/c11-2-1(21)3(12)6(15)4(2,13)8(17)5(2,14)7(3,16)9(6,18)10(8,19)20

InChI key

LHHGDZSESBACKH-UHFFFAOYSA-N

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General description

Chlordecone is a chlorinated cyclodiene pesticide and a persistent environmental contaminant, obtained via degradation of mirex.

Application

Chlordecone may be used as an analytical reference standard for the quantification of the analyte in animals using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Development and validation of an HPLC-MS/MS method with QuEChERS extraction using isotopic dilution to simultaneously analyze chlordecone and chlordecol in animal livers
Saint-Hilaire M, et al.
Food Chemistry, 252, 147-153 (2018)
Toxicological Study of Pesticides in Animals (1990)
High-performance liquid chromatography separation of chlordecone and its metabolites
Chromatographia, 22(1-6), 165-167 (1986)
Laurence Guldner et al.
Environmental research, 110(2), 146-151 (2009-12-17)
Chlordecone, an environmentally persistent organochlorine insecticide used intensively in banana culture in the French West Indies until 1993, has permanently polluted soils and contaminated foodstuffs. Consumption of contaminated food is the main source of exposure nowadays. We sought to identify
Richard C Scheri et al.
Toxicology letters, 191(1), 20-25 (2009-08-12)
Pretreatment of male C57BL/6 mice with low doses of the persistent organochlorine pesticide, chlordecone (CD), stimulated biliary excretion of exogenous cholesterol (CH) up to 3-fold. Increased biliary excretion occurred without changes in hepatic ATP-binding cassette transporter G8 (ABCG8) of the

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