43340

1,1,3,3-Tetramethyl-1,3-diphenyldisilazane

for GC derivatization, LiChropur^™

• Synonym(s): 1,3-Diphenyl-1,1,3,3-tetramethyldisilazane, DPTMDS
• Linear Formula: [C₆H₅Si(CH₃)₂]₂NH
• CAS Number: 3449-26-1
• Molecular Weight: 285.53
• Beilstein/REAXYS Number: 2738118
• EC Number: 222-372-5
• MDL number: MFCD00042916
• UNSPSC Code: 41116105
• PubChem Substance ID: 329756334
• NACRES: NA.22

Properties

• grade: derivatization grade ((GC derivatization)); for GC derivatization
• Quality Level: 100
• assay: ≥97.0%
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Silylations
• technique(s): gas chromatography (GC): suitable
• refractive index: n20/D 1.538 (lit.); n20/D 1.538
• bp: 96-100 °C/0.1 mmHg (lit.)
• density: 0.985 g/mL at 25 °C (lit.)
• SMILES string: C[Si](C)(N[Si](C)(C)c1ccccc1)c2ccccc2
• InChI: 1S/C16H23NSi2/c1-18(2,15-11-7-5-8-12-15)17-19(3,4)16-13-9-6-10-14-16/h5-14,17H,1-4H3
• InChI key: HIMXYMYMHUAZLW-UHFFFAOYSA-N

Description

General description

1,1,3,3-Tetramethyl-1,3-diphenyldisilazane (DPTMDS) is a derivatizing agent.

Application

DPTMDS may be used as ink to pattern semiconductor surfaces using Dip-Pen Nanolithography.[1] It may also be used to deactivate the retention gap during GC-MS analysis of trimethylsilyl derivatives.[2]

Other Notes

For the deactivation of glass capillary columns by persilylation [3][4]; The lithium amide is used for the selective formation of (Z)-enolates from ketones [5]

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter