41244

N-Desmethyl ofloxacin

analytical standard

• Synonym(s): 9-Fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• Empirical Formula (Hill Notation): C₁₇H₁₈FN₃O₄
• CAS Number: 82419-52-1
• Molecular Weight: 347.34
• Beilstein/REAXYS Number: 4890029
• MDL number: MFCD00871868
• UNSPSC Code: 12352200
• PubChem Substance ID: 329756078
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥96.5% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• mp: 256-262 °C
• application(s): clinical testing
• format: neat
• InChI: 1S/C17H18FN3O4/c1-9-8-25-16-13-10(15(22)11(17(23)24)7-21(9)13)6-12(18)14(16)20-4-2-19-3-5-20/h6-7,9,19H,2-5,8H2,1H3,(H,23,24)
• InChI key: WKRSSAPQZDHYRV-UHFFFAOYSA-N

Description

General description

N-Desmethyl ofloxacin is one of the active metabolites of ofloxacin, a drug prescribed for treating bacterial infections (effective against both Gram-positive and Gram-negative bacteria) that acts by inhibiting the enzyme DNA gyrase.[1]

Application

N-Desmethyl ofloxacin may be used as an analytical reference standard for the determination of the analyte in biological samples by high-pressure liquid chromatography with fluorescence detection[1] and capillary electrophoresis using laser-induced fluorescence detection technique.[2]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable